Spay / neuter clinic · 417 1/2 E Maxan Street, Port Isabel, TX 78578
Checked Oct 21, 2026 on the clinic's website · How we check
The short version
Nonprofit clinic in Port Isabel with low-cost spay and neuter by appointment and a weekly wellness clinic. Open Tuesday, Thursday, Friday and Saturday, noon to 4pm. No flat-faced breeds.
Appointment only, no walk-ins
2 rules on which pets they take: see below
No prices on their site: ask when you call
Who can use it
Their site doesn't say. Ask when you call.
No flat-faced breeds (Shih Tzus, Boxers, Bulldogs, Pugs, Persian cats); call with breed questions
Pets must be free of fleas and ticks and on prevention; you are charged if fleas or ticks are found
How to get in
Fill out the online surgery form. The clinic calls you as your date gets close.
Spay / neuter clinic · 500 E. Hackberry Ave, Suite 100-B, McAllen
Cat spay/neuter $89
Nonprofit spay and neuter clinic in McAllen, by appointment. Dogs $125, cats $89, with a non-refundable deposit to book. Drop off 7:30 to 8am, pick up 3 to 3:30pm.
Spay / neuter clinic · 2451 N US Expressway 281, Edinburg
Cat spay/neuter $75
Three spay and neuter days each month in Edinburg for Rio Grande Valley residents. Cats from $75, dogs from $100. Sign-up opens at 10am on the 1st of each month and fills fast.
Trap, spay or neuter and return for outdoor community cats in Edinburg, McAllen and nearby areas. On hold until the shelter hires a vet. Call or text (956) 249-0117.